Hydroa vacciniforme-like EBV-positive cutaneous T-Cell lymphoma, first report of 2 cases in Ecuador

Abstract:

Hydroa vacciniforme-like cutaneous lymphoma is a very rare Epstein-Barr virus positive peripheral T-cell lymphoma affecting Asian and Hispanic children and young adults with a defective cytotoxic immune response to EBV pbkp_redisposing to the development of the disease. We report on 2 Ecuadorian patients with papulovesicular and ulcerated crusted lesions on the face, upper and lower extremities and abdomen, with aggressive clinical course and, in one case, a fatal outcome. The histological and molecular profiles (immunohistochemistry and in situ hybridization) established a diagnosis of hydroa vacciniforme-like Epstein-Barr virus-encoded small RNAs + cutaneous T-cell lymphoma in both cases.

Año de publicación:

2016

Keywords:

• hydroa vacciniforme-like cutaneous T-cell lymphoma
• Epstein Barr virus (EBV)
• ECUADOR

Fuente:

scopus