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Hyperuricemia as a risk factor for obesity in adults from the city of Maracay, Venezuela

Abstract:

Introduction: Obesity is recognized as one of the most important problems of public health today, the hyperurcemia has been considered a risk factor for obesity, the main objective of this research was to assess hyperuricemia and other risk factors for obesity in patients of a nutrition consultation of a franchise in the city of Maracay, Aragua, Venezuela, 2013. Materials and Methods: Was a descriptive, cross-sectional, randomized study in 240 individuals of both sexes. Logistic regression model adjusted for obesity was performed by sex, age groups, personal history of hypertension, type 2 diabetes mellitus, blood glucose, total cholesterol, HDL-C, LDL-C, triglycerides and uric acid. Results: The prevalence of obesity in individuals of both sexes was 49,6% (women: 48,9%, male: 52,0%) and 34,2% overweight (women: 35,3%; Female: 30,0%).After adjustment of independent variables for obesity, the greater risk factor for obesity was uric acid (tertiles), where tertile 3 had two times higher risk of occurrence of obesity compared to tertile 1 (OR: 2,27 95% CI: 1,16 to 4,45; p=0,01). Conclusions: A high prevalence of obesity in patients attending nutrition consultation was determined; the elevated uric acid was the main risk factor found for obesity. The design and implementation of major studies evaluating obesity and hyperuricemia in order to establish specific therapeutic targets is recommended.