Regresar

Hyperuricemia validation for preeclampsia pbkp_rediction

Abstract:

Background: Uric acid is a marker for kidney damage and has been shown as a maternal neonatal risk factor in the physiopathology of preeclampsia. Objective: To determine the diagnostic validity of hyperuricemia for the prognosis of preeclampsia in pregnant women attending the Pablo Jaramillo Crespo Foundation in Cuenca-Ecuador, during 2016. Materials and Methods: Validity study of diagnostic test. The sample consisted of 185 pregnant women, users of the Pablo Jaramillo Crespo Foundation. In all cases, the uric acid value was determined using a COBAS C 111 analyzer and it was compared with the diagnosis of preeclampsia based on international recommendations. The data was analyzed on SPSS v. 15. Descriptive statistics, sensitivity, specificity, positive and negative pbkp_redictive values, and positive and negative probability coefficients were calculated for each cut-off point for the uric acid. Results: The mean in relation to age was 28.2 years old; 19 pregnant women had preeclampsia (10.3%). The mean value for uric was 4.16mg/dl. The best diagnostic efficiency corresponds to a uric said score > 5 (IJ: 0.88), with a sensitivity of 100%, specificity of 88%, PPV of 48.7%, NPV of 100%, LR+ of 8.3 and LR-of 0.0. Conclusion: Uric acid is valid for the diagnosis of preeclampsia, a value of 5mg/dl or more has the best diagnostic efficiency.