Immature granulocytes: Reference values, using the sysmex XE-2100 blood counter

Abstract:

Introduction: Automated hemograms have undergone numerous technical innovations during the last years. The immature granulocytes count, based on differences in membrane composition and on their higher levels of RNA, is a new parameter in the differential blood cell count. Its advantages include a rapid processing time and low cost. For it to be used as a parameter for clinical analysis, it becomes essential to establish reference «healthy» values so potentially pathological levels can be identified. Material and methods: A descriptive epidemiological survey was performed on a convenience sample of 708 hemograms selected from adults of both sexes and ages ranging from 18 to 60 years submitted to Net-Lab SA (Quito-Ecuador), received as part of routine health checkups during January and February 2009. We used the blood counter Sysmex XE-2100®. Results: The average age of the subjects studied was 34.18±11.7 years, and 64.4% of the subjects were males. Among this apparently healthy population, the reference absolute counts calculated for immature granulocytes ranged between zero and 0.03 x10 3/mm 3, and the relative counts were between zero and 0.4%, without significant differences by gender. Conclusions: These results were similar to the values reported in a German study made with an «a priori» methodology in healthy blood donors in the University Hospital of Leipzig. Thus, the reference values we identified may be generalizable to other populations.

Año de publicación:

2010

Keywords:

Fuente:

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