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Influence of FIO2 on PaCO2 During Noninvasive Ventilation in Patients with COPD: What Will Be Constant Over Time?

Abstract:

Influence of FIO2 on PaCO2 During Noninvasive Ventilation in Patients with COPD: What Will Be Constant Over Time? number of measures can be taken to optimize the conditions of extubation, eg, steroid pretreatment, optimization of fluid balance, glucose control, and nutrition support. These patients could also be targeted for interventions such as aggressive bronchial hygiene protocols, early mobilization, and careful titration of analgesics. The prediction of early versus late reintubation includes different variables, suggesting that different characteristics contribute to failure and potentially via different pathways. Our prediction models suggest that residual hypoxemia on the prediction day, likely representative of underlying pulmonary disease or other comorbidities, can predispose patients to the risk of failed extubation also in a nonimminent period. In terms of accuracy of prediction, our models of early and late …