Influence of pill burden and drug cost on renal function after transplantation

Abstract:

Study Objective To determine the influence of pill burden and drug cost on outcomes after renal transplantation. Design Retrospective medical record review. Setting Kidney and pancreas transplantation center. Patients Sixty‐eight adults who underwent kidney or kidney‐pancreas transplantation during 2007. Measurements and Main Results The median pretransplantation pill burden was 15 pills/day, which increased to 25 pills/day at 1 month after transplantation and returned to 16 pills/day by 1 year after transplantation. Pretransplantation pill burden was lower than the burden at 1, 3, 6, 12, and 24 months after transplantation (p<0.05). The mean pretransplantation drug cost of $1918/month was lower than the cost at 1 month after transplantation ($2564/mo, p=0.04) but was similar thereafter. Higher pretransplantation pill burden was associated with increased serum creatinine concentration at 6 months after …

Año de publicación:

2012

Keywords:

Fuente:

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