L-α-Methylhomoisoserine: A New Versatile Building Block for Peptide and Depsipeptide Modification

Abstract:

An efficient access to L-α-methylhomoisoserine derivatives starting from L-citramalic acid is described. The new compounds are GABA derivatives and represent new, versatile building blocks for peptide and depsipeptide modification.

Año de publicación:

2003

Keywords:

• Amino acid hydroxamates
• Curtius rearrangement
• Hexafluoroacetone
• γ-amino-α-hydroxy-α -methylbutyric acid
• Arndt-Eistert synthesis
• Wolff rearrangement
• Citramalic acid

Fuente:

scopus

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