Lack of diabetes in rural Colombian Amerindians

Abstract:

The prevalence of impaired glucose tolerance (IGT) and NIDDM varies widely between different subpopulations of Amerindians. Thus, it is low (~ 2%) in rural Chilean Mapuche Indians and very high (~ 65%) in urbanized Pima and Papago Indians of Arizona (1). Historical, linguistic, and genetic evidence suggests that Colombian Indians have a common evolutionary relationship with Pima and Mapuche Indians (2-4). It was therefore of interest to examine the prevalence of abnormal glucose tolerance in rural Colombian Amerindians from four tribes (Arhuaco, Arzario, Kogui, and Wayuu) based in separate settlements. The study was performed as part of a population genetics study. At each settlement, all subjects above the age of 18 years were invited to participate, there being no other exclusion criteria. The overall response rate was estimated to be~ 48%. Subjects were given a 75-g oral glucose load after an …

Año de publicación:

1996

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Fuente:

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