Multivariate statistical analysis to detect insulin infusion set failure
Abstract:
Multivariate statistical analysis techniques are applied to insulin infusion set failure detection (IISF), a challenging problem faced by individuals with type 1 diabetes that are on continuous insulin infusion pump therapy. Bivariate classification (BC), principal component analysis (PCA), and a combined approach were applied to simulated glucose concentrations for 10 patients, based on a nonlinear physiological model of insulin and glucose dynamics. The PCA algorithm had fewer false alarms than BC, while detecting most drifting (ramp) infusion set failures before complete failure occurred. © 2011 AACC American Automatic Control Council.
Año de publicación:
2011
Keywords:
Fuente:
scopus
Tipo de documento:
Conference Object
Estado:
Acceso restringido
Áreas de conocimiento:
- Diabetes
Áreas temáticas:
- Enfermedades