N-Triethylene glycol (N-TEG) as a surrogate for the N-methyl group: Application to Sansalvamide A peptide analogs


Abstract:

Here we studied the N-triethylene glycol (N-TEG) group as a surrogate for the N-Me group in Sansalvamide A peptide. The five N-TEG and N-Me analogs of this cyclic pentapeptide were synthesized, and their biological activity, lipophilicity and conformational features were compared. © 2013 The Royal Society of Chemistry.

Año de publicación:

2013

Keywords:

    Fuente:

    googlegoogle
    scopusscopus

    Tipo de documento:

    Article

    Estado:

    Acceso restringido

    Áreas de conocimiento:

    • Péptido
    • Bioquímica

    Áreas temáticas:

    • Química orgánica