N-Triethylene glycol (N-TEG) as a surrogate for the N-methyl group: Application to Sansalvamide A peptide analogs
Abstract:
Here we studied the N-triethylene glycol (N-TEG) group as a surrogate for the N-Me group in Sansalvamide A peptide. The five N-TEG and N-Me analogs of this cyclic pentapeptide were synthesized, and their biological activity, lipophilicity and conformational features were compared. © 2013 The Royal Society of Chemistry.
Año de publicación:
2013
Keywords:
Fuente:


Tipo de documento:
Article
Estado:
Acceso restringido
Áreas de conocimiento:
- Péptido
- Bioquímica
Áreas temáticas:
- Química orgánica