Neuropatía autonómica cardiovascular diabética

Abstract:

Diabetic cardiovascular autonomic neuropathy (CAN) is defined as an alteration in the autonomous control of the cardiovascular system in a diabetic patient diagnosed after excluding other causes. CAN is caused by damage to peripheral autonomous nerve fibers that innervate to the heart and blood vessels, which alters control of heart rate and vascular dynamics. CAN is common in diabetics, estimated to have 7% of patients with Diabetes Mellitus (DM). The CAN is an underdiagnosed complication that affects multiple organs and is associated with cardiovascular disease (CVD), chronic kidney disease (CKD) and morbidity and mortality of patients with DM. Clinical manifestations of CAN are orthostatic hypotension, resting tachycardia, exercise intolerance, silent myocardial infarction and intraoperative cardiovascular risk. Risk factors for developing NAC are age, sex, BMI, duration of diabetes, glycemic control, cardiovascular risk profile and microvascular complications. An update on the epidemiology, pathophysiology, clinical manifestations, diagnosis and treatment of CAN is presented.

Año de publicación:

2022

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Fuente:

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