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New algorithm for QT dispersion analysis in XYZ-lead holter ECG. Performance and applications

Abstract:

In this paper a new algorithm for automatic analysis of QT dispersion (QTd) in three-lead (X, Y, Z) Holler ECG records is presented. To evaluate its performance we have compared automatic with manual annotations, using a set of 1000 beats of Holter ECG records from the IDEAL Data Base. The signals have been automatically analyzed and the same beats have been analyzed by two cardiologists. The results obtained show that the reproducibility of the automatic QTd measurement is comparable to manual. QTd has been studied as a discriminator of patients with Dilative Cardiomyopathy from healthy subjects. We have found that QTd in 24 hours presents statistically significant differences when comparing subjects from those two groups. We have analyzed also mean and standard deviation of RR, QT and QTc intervals to determine their statistical significance in discriminating subjects from both groups.