New and efficient synthesis of 6,11-dihydro-11-ethyl-5H-dibenz[b,e]azepine derivatives starting from N-benzylanilines via amino-Claisen and Friedel-Crafts methodologies

Abstract:

New and efficient synthesis of 6,11-dihydro-11-ethyl-5H-dibenz[b,e]azepine derivatives, using the key steps of BF3·OEt 2-catalyzed aromatic amino-Claisen rearrangement and the intramolecular alkene Friedel-Crafts alkylation, is reported.

Año de publicación:

2004

Keywords:

• N-allylation
• Intramolecular alkene Friedel-Crafts alkylation
• Amino-Claisen rearrangement
• Dibenz[b,e]azepine derivatives

Fuente:

scopus