New guanidine alkaloids from the leaves of Verbesina peraffinis

Abstract:

Two new guanidine alkaloids, 1 and 2, were isolated from the methanol extract of the leaf of Verbesina peraffinis, in addition to four known substances: galegine, the methylamide of caffeic acid, galactitol and the flavonoid 3-O-glucosyl-(1-2)-galactoside-5,7,4′ trimethoxy-kaempferol. Their structures were determined on the basis of spectroscopic methods. The antihypertensive activity of the methanolic extract was assayed in rats using a model of hypertension induced by footshock.

Año de publicación:

2008

Keywords:

• Caffeic amide
• Verbesina peraffinis
• Guanidine alkaloids
• Moraceae

Fuente:

scopus