Non-alcoholic fatty liver disease (NAFLD): Review and update. Working group of the latinamerican society of pediatric gastroenterology, hepatology and nutrition (LASPGHAN)

Abstract:

Summary Along with obesity, non-alcoholic fatty liver disease, and its progression to esteatohepatitis, have become the most frequent liver disease among children and teenagers. Since cirrhosis could be an outcome of this condition, it is urgent to test for it in overweight and obese patients. Objectives. To compile in a single article strategies for clinical coaching and handling of children with this condition. On the basis of this revision, to promote research projects. Methods. SLAGHNP/LAPSGHAN, under responsibility and supervision of an editor/coordinator who chose contents and references with the best evidence, called its associates to perform this revision, after which edition and unification of the contents proposed. Results. The severity of EHGNA/ EHNA is established as a new infant liver disease and the lack of information on it in Latin America is noted unlike the United State, where its status as the most prevalent hepatopathy among children has been already established. Usefulness of blood chemistry tests and images is emphasized; although it has not been established when it should be recommended, it is clear liver biopsy is the gold standard for detecting the disease. Conclusions. It is important to start in Latin America research and follow-up programs on this disease, whose rapid progression will be continentwise a public health concern in the near future. A latin american register should be started under leadership of SLAGHNP/LAPSGHAN to establish this liver disease's epidemiology, establish a clinical diagnosis and choose adequate complimentary tests to confirm diagnosis.

Año de publicación:

2016

Keywords:

• Non alcoholic fatty liver disease
• Non alcoholic steatohepatitis
• CHILDREN
• Adolescentes
• Metabolic syndrome

Fuente:

scopus