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O-172 Evaluation of the effect of a topical anaesthetic/antiseptic formulation for the treatment of contagious ecthyma in lambs on the concentration of serum amyloid A

Abstract:

Contagious ecthyma (CE), caused by the orf virus, is a highly contagious eruptive skin infection of sheep and goats, which mainly affects young animals. In Spain, the vaccine for this disease is not available, and treatment involves standard hygiene practices and antibiotics to control secondary infections, which can increase the risk of antimicrobial resistance. There is a need for alternative treatments to improve the welfare of affected animals and control the spread of the disease. This study evaluated the effectiveness of a topical anaesthetic/antiseptic formulation, Tri-Solfen®(TS, Bayer Animal Health, Gordon, NSW, Australia), containing the local anaesthetics lignocaine and bupivacaine, plus adrenalin and an antiseptic (cetrimide) for the treatment of CE in lambs. The evolution of the concentration of the major acute phase protein serum amyloid A (SAA) was assessed in lambs experimentally infected with the orf …