O4‐06‐02: Frailty is Associated with Subjective Cognitive Decline in Older Female Adults without Dementia: The Vanderbilt Memory & Aging Project

Abstract:

Background Subjective cognitive decline (SCD) pbkp_redicts cognitive progression and diagnostic conversion and may represent early changes across the cognitive spectrum. Physical frailty represents a loss of physiological reserve and is associated with cognitive impairment and incident dementia. We hypothesized that early frailty markers are associated with increased SCD. Methods Participants with normal cognition (n= 164, 60% male) and mild cognitive impairment (n= 165, 59% male) were drawn from the Vanderbilt Memory & Aging Project, a case-control cohort. Markers of frailty (gait speed, grip strength, exhaustion, physical activity) were measured using standard methods and a composite frailty score was calculated by averaging the individual component z-scores. SCD was quantified using a multi-questionnaire protocol, including a total SCD inventory and the Everyday Cognition Scale (ECog). Proportional …

Año de publicación:

2016

Keywords:

Fuente:

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