Overview on the drug development process and molecular similarity-based virtual screening techniques
Abstract:
Drug development is a very complex task but also very appreciated by the sensibility that generates the negative impact of diseases in modern society. In this review, we will address the general characteristics of the traditional paradigm of drug development pipeline. Later, virtual screening techniques will be introduced as a rational and complementary alternative to the early stages of this process. In this sense, we will focus on similarity searching and its key components.
Año de publicación:
2013
Keywords:
- Similarity searching
- Virtual screening techniques
- Drug development process
- Molecular similarity
Fuente:
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Tipo de documento:
Review
Estado:
Acceso restringido
Áreas de conocimiento:
- Farmacología
Áreas temáticas:
- Farmacología y terapéutica
- Sistemas fisiológicos específicos de los animales