P1‐207: A Competitive Queuing Analysis of Visual Working Memory Deficits in Non‐Demented Older Adults: the Vanderbilt Memory and Aging Project

Abstract:

Background Competitive queuing (CQ) models of working memory (WM) posit two hierarchical mechanisms:(1) excitatory parallel planning responsible for item activation; and (2) inhibitory competitive choice/response suppression responsible for item recall followed by item suppression. The current research sought to dissociate these mechanisms using a visual WM task in participants with mild cognitive impairment (MCI) and normal cognition (NC). Methods NC (n= 124), single-domain amnestic MCI (aMCI; n= 58) and multi-domain MCI participants (mMCI; n= 45) were drawn from the Vanderbilt Memory & Aging Project, a case control study. Participants completed a comprehensive neuropsychological protocol, including Symbol Span, a visual WM task. Outcome measures included (1) age-corrected scale score,(2) ANY ORDER recall (regardless of correct serial position) assessing CQ parallel processing, and (3 …

Año de publicación:

2016

Keywords:

Fuente:

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