P2-198 Overweight associated with non-atopic wheeze in rural tropics

Abstract:

Introduction The parallel rise in prevalence of asthma and overweight/obesity in some Latin American countries has led to suggestions of a link between the two epidemics. The aim of this study was to explore the effects of being overweight on wheeze, exercise-induced bronchospasm and atopy. Methods A case-control study was conducted among 809 Afro-Ecuadorian children aged 7–19 yrs living in rural communities in tropical Ecuador. Asthma cases were selected based on the presence of recent wheeze and controls as a random sample of those without symptoms by questionnaire. Atopy was measured either by the presence of allergen specific IgE (asIgE) in serum or by allergen skin test reactivity (SPT). Overweight children were those with a Body Mass Index (BMI) ≥ +1 z-score based on WHO growth curves (2007). Results Comparing atopic vs non-atopic children, the prevalence of SPT (adj. OR 2.12, 95 …

Año de publicación:

2011

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