PRM204-PSYCHOMETRIC EVALUATION OF EORTC QLQ-C30 IN CUBAN PATIENTS WITH ADVANCED NON-SMALL CELL LUNG CANCER

Abstract:

Objectives To assess, by item response theory (IRT) and confirmatory factor analysis (CFA), the psychometric characteristics of the EORTC QLQ-C30. Methods We analyzed responses to QLQ-C30 from 1107 patients with advanced lung cancer who were included in five clinical trials. We used nonparametric Mokken analysis in a training sample (n= 332) to preliminary assess the dimensional structure of the QLQ-C30. We then used CFA in the test sample (n= 775) to confirm the measurement dimensions. We also used a parametric IRT (Samejima's graded response model) to evaluate the difficulty and discrimination of the ítems. Results The Mokken analysis showed QLQ-C30 represents a unidimensional scale. All items showed adequate scalability indexes (Loevinger’s index> 0.30), and the overall scalability of QLQ-C30 was 0.47, defining a medium scale. The unidimensionality of the QLQ-C30 was confirmed by …

Año de publicación:

2018

Keywords:

Fuente:

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