A POSSIBLE ROLE OF EXTRACELLULAR MATRIX MOLECULES IN THE IMMUNE RESPONSE OF GILTHEAD SEABREAM Sparus aurata L.

Abstract:

The gilthead seabream (Sparus aurata L., Teleostei) is a protandrous hermaphrodite, seasonal breeding sparid fish that undergoes sex change during the second or third year of life, depending on the natural environment. The aquaculture of this specie is an important industry widely spread in the Mediterranean area. Our group is especially interested in the study of the immune and reproductive systems in this fish model, emphasizing in the processes and molecules involved. It was described that some matrix metalloproteinases (MMPs), such as MMP2, MMP3, MMP9, MMP13 and MMP25, are involved in the immune response in mammals. Its expression can be modulated in the presence of cytokines and its receptors, taking part in the inflammatory activation pathways. However, the role of MMPs in bony fish is largely unknown.

Año de publicación:

2009

Keywords:

Fuente:

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