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Prevalence of HPV and risk factors in a population of symptomatic and asymptomatic women university, Ecuador 2020

Abstract:

The human papillomavirus or HPV represents one of the most common sexually transmitted diseases, the main cause of cervical cancer. Objective. Determine the prevalence of genital HPV infections, identify clinical-epidemiological factors associated with said prevalence and obtain the frequency of viral types in symptomatic and asymptomatic women university in Ecuador, year 2020. Methodology. Descriptive, cross-sectional, experimental field research, the population consisted of 155 students aged between 18-28 years. As a data collection instrument, a survey on clinical factors was carried out, the detection of HPV was by polymerase chain reaction (PCR), amplifying a section of 450 base pairs of the viral genome belonging to the L1 fragment, the detection of the genotype of HPV was performed by studying the restriction fragment length polymorphism (RFLP). Outcome. An HPV prevalence of 15.56% (21/135) was found, the age the highest prevalence was found in women 24-28 years (57.14%), 19.05% (4/21) of women who had pregnancies came out HPV (+), referring to symptoms, 60.00% were symptomatic and 40.00% asymptomatic, of which 20.37 (11/54) were HPV (+). High-risk HPV DNA sequences were detected in 66.67% (8/12). Integrated knowledge of all these factors or elements that involve the patient as a social and biological entity, the virus and possible co-factors is essential for the implementation of prevention programs (educational and prophylactic) and for the optimal management of available resources in the treatment and monitoring of the different levels of this pathology.