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Prevalence of combinations of metabolic syndrome components in the municipality of San Cristóbal, Táchira, Venezuela

Abstract:

Introduction: Metabolic syndrome (MS) is defined as a set of risk factors that increase the likelihood of developing type 2 diabetes mellitus (T2DM) and cardiovascular disease. However, in our town not studied the behavior of combinatorial criteria for MS, so the aim of this study was to determine the prevalence of combinations of components of MS in the municipality of San Cristobal, Venezuela. Materials and methods: This was a cross-sectional study with a multistage and randomized sampling on 362 individuals of both sexes, who were identified as components MS by IDF/AHA/NHLBI/WHF/IAS/IASO (2009) criteria’s. The presence of insulin resistance (IR) was assessed by HOMA2-IR. Results: The prevalence of MS was 51,4% (n=186) for the general population. The most frequent MS cluster was that included all the criteria 16,1% (n=30); followed by the presence of AO-HBP-LowH-ET (AO: abdominal obesity, HBP: High blood pressure or hypertension, Low-H: low HDL-C and ET: Elevated TAG) combinatorial 12,4% (n=23). The combinatorial AO-HBP-HG-ET (AO: abdominal obesity, HBP: High blood pressure or hypertension, HG: Hyperglycemia or T2DM: Elevated TAG) was the one with higher frequency of IR with 60,0% followed by AO-HBP-LowH-ET presented 43,48% of IR and followed by all criteria with a prevalence similar IR of 43.33%. Conclusions: The MS showed a high prevalence in our population. Combinatorial frequently were the criteria presented elevated waist circumference, while less frequent lacked it. Similarly combinations with abdominal obesity were those that showed increased insulin resistance.