R(st) calc: A collection of computer programs for calculating estimates of genetic differentiation from microsatellite data and determining their significance

Abstract:

R(ST), an analogue of F(ST), provides a convenient approach for estimating levels of genetic differentiation from microsatellite data. This paper examines current approaches for calculating estimates of R(ST) and suggests a weighting scheme based on the transformation of allele sizes at loci across data sets. Combined within an analysis of variance framework this scheme yields an estimator of R(ST) analogous to the θ estimator of F(ST). Software for the IBM-PC is described which carries out such calculations and assesses the significance of R(ST) or Nm estimates using bootstrap and permutation tests.

Año de publicación:

1997

Keywords:

• Microsatellite
• Permutation test
• Genetic differentiation
• R(ST)
• Bootstrap
• Analysis of Variance

Fuente:

scopus