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Rates of adverse reactions to first and second doses of BCG vaccination: Results of a large community trial in Brazilian schoolchildren

Abstract:

OBJECTIVE: To evaluate the incidence of adverse reactions to first and second bacille Calmette-Guérin (BCG) vaccination in schoolchildren. SETTING AND DESIGN: Enhanced surveillance in a Brazilian trial. Suspected reactions were reported to a nurse who visited cases and completed a standard form. RESULTS: Among 71341 schoolchildren studied, 33 reactions were reported. Of these, 25 fulfilled the criteria, resulting in a rate of one per 2854 vaccinations, with no deaths or BCG-osis. Reactions to second doses were more common than to first BCG vaccinations, but this difference was not statistically significant. CONCLUSIONS: Adverse reactions to a second dose of BCG may be more frequent than reactions to a first dose, but they are still rare events.

Año de publicación:

2003

Keywords:

  • ADVERSE REACTIONS
  • BCG vaccine
  • BCG-REVAC

Fuente:

scopusscopus

Tipo de documento:

Article

Estado:

Acceso restringido

Áreas de conocimiento:

  • Salud Pública
  • Epidemiología

Áreas temáticas:

  • Medicina forense; incidencia de enfermedades
  • Problemas sociales y servicios a grupos
  • Ginecología, obstetricia, pediatría, geriatría

Contribuidores:

Ichihara M.Y.T.Ichihara M.Y.T.
Dourado M.I.Dourado M.I.
Mauricio L. BarretoMauricio L. Barreto
Rodrigues L.C.Rodrigues L.C.
Bierrenbach A.L.Bierrenbach A.L.
Rios M.Rios M.
Cunha S.S.Cunha S.S.
Goes J.Goes J.
Pereira S.M.Pereira S.M.