Regular exercise attenuated lipid peroxidation in adolescents with Down's syndrome

Abstract:

Objectives: This study was designed to ascertain whether regular exercise may attenuate lipid peroxidation in adolescents with Down's syndrome. Materials and methods: Thirty-one male adolescents with Down's syndrome performed a 12-week training program, 3 days/week at a work intensity of 60-75% of peak heart rate (HRmax = 194.5-[0.56 age]). Plasmatic malondialdehyde (MDA) was determined by high performance liquid chromatography (HPLC). Results: When compared to baseline, MDA content was decreased significantly. Conclusion: Regular exercise significantly decreased lipoperoxidation in Down's syndrome. © 2006 The Canadian Society of Clinical Chemist.

Año de publicación:

2007

Keywords:

• Down's syndrome
• Malondialdehyde
• Exercise
• Lipid peroxidation

Fuente:

scopus