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Relación entre anemia del paciente con nefropatía diabética y hemoglobina glicosilada en el Hospital José Carrasco Arteaga. Cuenca – 2013

Abstract:

Background: glycosylated hemoglobin is a test often used in the evaluation of diabetes mellitus. It is not known what would be the effectiveness of the test in patients with diabetic nephropathy and chronic kidney disease (CKD) who have anemia. Objective: to determinate relationship between the presence of anemia and glycosylated hemoglobin valuesin patients with diabetic nephropathy and CKD in José Carrasco Arteaga Hospital of Cuenca in 2013. Methodological design: this is an analytical, quantitative, cohort study. The sample was composed with 135 patients, 41 had anemia (exposed cohort) and 94 without anemia (unexposed cohort) . The main variables analyzed were the presence of anemia and levels of glycosylated hemoglobin. The data was obtained through an interview with the patients and their digital clinical history, based on which, a form is filled, after the information was transferred to the computer for further analysis with Excel Microsoft , SPSS, Minitab15 programs. Results: the mean value of the glycosylated hemoglobin was 8.3 % in the total number of individuals included in the study, whereas in the group with anemia was 7.4 % and in the group without anemia turned 8, 7%, a difference that was statistically significant ( p < 0.05 ) , in addition to also establish a cause- effect , patients with anemia have most likely lower glycosylated Hb values compared to patients without anemia ( RR > 1 CI 1.02 to 6.73 , p < 0.05). The validity of the glycosylated hemoglobin test, used to monitor the control of diabetes mellitus and CKD may be diminished if a patient develops anemia Conclusion: it was determined that patients with anemia have lower glycosylated hemoglobin values. The utility of this test may be decreased in controlling the anemic patient with diabetes mellitus and CKD. KEY WORDS: GLYCOSYLATED HEMOGLOBIN A, CHRONIC KIDNEY FAILURE, DIABETES MELLITUS, ANEMIA, DIABETIC NEPHROPATHY.