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A closer look to polyesters: Properties, synthesis, characterization, and particle drug delivery applications

Abstract:

Background: Natural and synthetic polymeric materials can be used in the fields of bio-medicine and pharmaceuticals as a material for controlled drug delivery. Among the synthetic poly-mers, polyesters are synthesized from two natural monomers: lactic and glycolic acid, which are bio-compatible and biodegradable. Objective: Here, we review broad aspects of polyesters including its properties, synthesis, characteri-zation, and particle drug delivery applications. Conclusion: Finally, we have concluded that polyesters are certainly very versatile material that are continuously reinvented for future application in new areas of science and medicine. However, sev-eral aspects must be considered when synthesizing polyesters, which have a direct influence on bio-degradability and biocompatibility. These properties may limit the performance of in vitro and in vi-vo tests.