SAT-423 Anti-thyroid Drug Response in Graves’ Disease: Pbkp_redictors of Biochemically Persistent Disease


Abstract:

Introduction: Anti-thyroid Drugs (ATD) have become the most frequently used treatment for Graves’ disease (GD) in the United States. However, the response to this therapy is variable. Factors that pbkp_redict biochemically responsive vs. biochemically persistent disease remain unknown. Identifying pbkp_redictors of disease poorly responsive to ATD can help guide treatment decision making, follow up planning and prognosis. Methods: From a database of patients with GD treated with ATD and receiving care at an academic medical center between 2009–2019, we selected adults with incident GD treated with ≥14 days of ATD. Results: 172 patients (from a database of 730 patients with GD on ATD) were sampled for the purpose of this pilot and 97 of these met inclusion criteria. Patients had a median age of 50 (18–90); female, 70.1%; never smokers, 64.9%; median goiter size of 40 g (15 …

Año de publicación:

2020

Keywords:

    Fuente:

    googlegoogle

    Tipo de documento:

    Other

    Estado:

    Acceso abierto

    Áreas de conocimiento:

    • Medicina interna

    Áreas temáticas de Dewey:

    • Farmacología y terapéutica
    • Enfermedades