Regresar

Schizophrenia related genes and its molecular treatments: Systematic review and analysis

Abstract:

Schizophrenia is a mental disorder characterized by strong psychotic episodes of hallucinations and delusions, which affects, according to statistics, 1% of the world population. Although its pathogenesis remains unknown, multiple investigations suggest that several associations of chromosomal locus are responsible in the neurodevelopment of the disorder. This polygenic theory, shared by diseases such as cancer and diabetes, can also be influenced by environmental and epigenetic factors. Despite the existence of antipsychotic drugs that partially control the disease, these in many cases suppose counterproductive and ineffective effects. That is why a new research line on epigenetic factors and chromosomal associations, linked to the disorder origin, could lead to new pharmacological treatments that represent a real breakthrough.