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Self‐Assessment of Disability in Parkinson's Disease: The MDS‐UPDRS Part II Versus Clinician‐Based Ratings

Abstract:

Background Parkinson's disease (PD) is characterized by motor and nonmotor symptoms that progress with time, causing disability. The performance of a disease‐specific, self‐applied tool for assessing disability, the MDS‐UPDRS Part II, is tested against generic and rater‐based rating scales. Methods An international, cross‐sectional, observational study was performed. Patients were assessed with the Hoehn and Yahr (HY) and five disability measures: MDS‐UPDRS Part II, Schwab and England Scale (S&E), Clinical Impression of Severity Index‐PD (CISI‐PD) Disability item, Barthel Index (BI), and Rapid Assessment of Disability Scale (RADS). Data analysis included correlation coefficients, Mann‐Whitney and Kruskal‐Wallis tests, and intraclass‐correlation coefficient for concordance. Results The sample was composed of 451 patients, 55.2% men, with a mean age of 65.06 years (SD = 10.71). Disability …