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Severidad de presentación de acrocordones relacionada al riesgo cardiovascular medido en función de índice de masa corporal y obesidad central

Abstract:

Context: acrochordons are benign skin protrusions present in areas of friction; they usually accompany metabolic diseases.Ojective: to characterize the association between the severity of the presentation of acrochordons and the cardiometabolic risk measured according to the body mass index and central obesity in patients over 18 years of age who attend the San Francisco de Quito Hospital Dermatology Consultancy (HSFQ).Subjects and methods: patients of both sexes, over 18 years of age, who spontaneously go to the External Consultation of the Dermatology Service of the San Francisco de Quito Hospital, belonging to the Ecuadorian Social Security Institute, from September to October 2015 Main measurements: Family and personal history of the disease, measurement of weight, height, waist circumference and presence of acrochordons (coloration, number and location) associated with acanthosis nigricans.Results: 111 subjects were studied, with an average age of 47 years; female patients predominated (60.7%). A body mass index (BMI) greater than 30 kg / m2 was determined in 55.9% of cases, with phototype IV being the most common (59.4%) associated with abdominal obesity (69.3%). The most affected area is neck (96.4%); 75.6% of cases were classified as severe. The prevalence of acrochordons of mixed coloration and severe form of the disease was present in 39 patients (29%). A BMI ≥30 Kg / m2 and the severe form of acrochordons is considered a risk factor, without showing a statistical association (OR 1.83, 95% CI 0.76-4.41). Subjects with BMI ≥ 30 Kg / m2 have a higher risk of presenting acrochordons of severe form associated with acanthosis nigricans (OR 2.62, 95% CI 1.07-6.36).Conclusion: Statistical relationship was demonstrated in the group of patients with obesity and acrochordons of severe presentation, who presented associated acanthosis nigricans