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Sex-dependent performance of the neutrophil-to-Lymphocyte, monocyte-to-Lymphocyte, platelet-to-Lymphocyte and mean platelet volume-to-Platelet ratios in discriminating COVID-19 …

Abstract:

Background The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and mean platelet volume-to-platelet ratio (MPR) are combined hematology tests that pbkp_redict COVID-19 severity, although with different cut-off values. Because sex significantly impacts immune responses and the course of COVID-19, the ratios could be biased by sex. Purpose This study aims to evaluate sex-dependent differences in the contribution of NLR, PLR, MLR, and MPR to COVID-19 severity and mortality upon hospital admission using a sample of pneumonia patients with SARS-CoV-2 infection. Methods This single-center observational cross-sectional study included 3,280 confirmed COVID-19 cases (CDC 2019-Novel Coronavirus real-time RT-PCR Diagnostic) from Quito (Ecuador). The receiver operating characteristic (ROC) curve analysis was conducted to identify optimal cut …

Año de publicación:

2022

Keywords:

    Fuente:

    googlegoogle

    Tipo de documento:

    Other

    Estado:

    Acceso abierto

    Áreas de conocimiento:

    • Inmunología
    • Inmunología

    Áreas temáticas de Dewey:

    • Enfermedades
    • Fisiología humana
    • Salud y seguridad personal

    Contribuidores:

    MARTHA FORSMARTHA FORS