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Smartphone PPG Validation for a Depression Assessment Protocol

Abstract:

A new smartphone application for pulse photoplethysmography (PPG) recording is validated for a depression assessment protocol, consisting of four stages that includes recordings of movement-related tasks, talking-related tasks, and stillness. The separation of these stages allows to evaluate the agreement between the PPG acquired using the smartphone camera and a commercial pulse oximeter, used as reference, in different conditions. Several time-domain and frequency-domain heart rate variability (HRV) metrics have been studied. Results suggest a strong agreement during stillness phases (r ≥ 0.96 (p < 0.05) for all the HRV metrics), as well as a moderate downgrade during movement and talking. The agreement is also different between low-frequency related metrics (r ≥ 0.92 (p < 0.05)) and high-frequency related metrics (r < 0.78 (p < 0.05)). The overestimation of the high-frequency component of the HRV may be a limitation for smartphone PPG in depression monitoring.