Solution conformation of a pentapeptide by nmr and molecular modeling studies

Abstract:

High resolution NMR studies and molecular modeling calculations were performed on a linear pentapeptide BOC-Tyr-Gly-Gly-Pro-Leu-OMe. This molecule exhibits two conformations in the solution state. While the 13C spectrum in nonpolar solvents such as acetonitrile shows only one form, in DMSO-d6. © 1993, Taylor & Francis Group, LLC. All rights reserved.

Año de publicación:

1993

Keywords:

• cis-trans isomerization
• β-Turn
• Hydrogen bond
• molecular modeling
• 2D NMR

Fuente:

scopus