Studies directed to the synthesis of new C-5 spiroannulated julolidines

Abstract:

Two series of new 7,9-disubstituted spirojulolidines 8a-d and 10a-e were synthesized by acid catalyzed intramolecular cyclization of N-(3-chloropropanoyl) spirodihydroquinolines 5a-d and N-carbethoxymethyl spirodihydroquinolines 7a-e using AlCl3 and PPA, respectively. The spectroscopic analyses of intermediate compounds and the final spirojulolidines were discussed. © 2002 Elsevier Science Ltd. All rights reserved.

Año de publicación:

2002

Keywords:

• Spirojulolidine
• Spirolilolidine
• Intramolecular Friedel-Crafts alkylation

Fuente:

scopus