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Synthesis and structural study of 2‑(haloalkyl)‑3‑methylchromones

Abstract:

Abstract The novel 2-(difluoromethyl)-3-methylchromone, 2-(dichloromethyl)-3-methylchromone, and 3-methyl-2-(perfluoroethyl)chromone were synthesized by a one-pot method and characterized through MS spectrometry, cyclic voltammetry, and vibrational (IR, Raman), UV–Vis, fluorescence, and NMR (1H, 13C, and 19F) spectroscopy. The crystal structure of 2-(difluoromethyl)-3-methylchromone and 2-(dichloromethyl)-3-methylchromone determined by X-ray diffraction methods were used to calculate their intermolecular interactions and crystal lattice energies together with the Hirshfeld surface analysis. Graphic abstract

Año de publicación:

2019

Keywords:

    Fuente:

    googlegoogle

    Tipo de documento:

    Other

    Estado:

    Acceso abierto

    Áreas de conocimiento:

    • Química orgánica
    • Química general
    • Ciencia de materiales

    Áreas temáticas:

    • Química orgánica
    • Farmacología y terapéutica
    • Enfermedades

    Contribuidores:

    Luis Alejandro RamosLuis Alejandro Ramos