Synthesis of phosphorylated tripeptides representing poisoned acetylcholinesterase


Abstract:

Tripeptide sequences bearing dimethyl phosphate, dimethylphosphorothionate, and O,S-dimethylphosphorothiolate groups at the serine residue were synthesized to serve as active site models of organophosphate-poisoned acetylcholinesterase. © 1993.

Año de publicación:

1993

Keywords:

  • Glu-Ser-Ala
  • organophosphate
  • tripeptide

Fuente:

scopusscopus

Tipo de documento:

Article

Estado:

Acceso restringido

Áreas de conocimiento:

  • Bioquímica
  • Bioquímica
  • Bioquímica

Áreas temáticas:

  • Farmacología y terapéutica
  • Bioquímica
  • Química orgánica