Regresar

The Maracaibo city metabolic syndrome prevalence study: Primary results and agreement level of 3 diagnostic criteria

Abstract:

Objective: the purpose of this investigation was to determine the prevalence of Metabolic Syndrome (MS) and associated factors in the adult population of Maracaibo. Materials and Methods: This is a descriptive, crosssectional study, with a randomized multietapic sampling method, which recruited 2,230 individuals from both genders, 18 years and older. To diagnose MS, 3 definitions were used: the IDF-2009, IDF-2005 and ATPIII-2005; level of agreement was calculated using the k Cohen function and the Landis and Koch assessment scale. Finally, three logistic regression models were constructed to evaluate risk factors associated with each MS definition. Results: MS prevalence was 42.4%, 41.6% and 35.5% using IDF-2009, IDF-2005 and ATPIII-2005 respectively. Agreement level between IDF-2009 and ATPIII-2005 was k=0.86 (p<0,00001); between IDF-2005 and ATPIII-2005 was k=0.84 (p<0,0001); and between IDF-2005 and IDF- 2009 was k=0.98 (p<0,000001). The most prevalent metabolic component was abdominal obesity with 75.1% using IDF-2005/IDF-2009 and 48.9% with ATPIII-2005, Low HDL-C with 57.8% and high blood pressure with 38.38%. Multivariate analysis showed that age, insulin resistance, BMI, and CRP-us are risk factors for MS; HOMA b-cell function and leisure time physical activity resulted to be a protective factors for MS. Conclusions: MS in our population is one of the highest in the world. All 3 criteria showed a near-perfect agreement levels, probably due to the fact that 4 out of 5 components are identical; therefore the observed differences are due to differences in waist circumference cut-off points.