The microbiome in other mucosal sites

Abstract:

Culture-independent studies of the microbiome of mucosal sites other than the intestine are at an early and exciting stage. Mucosal surfaces are universally warm and moist and often contiguous with or adjacent to each other and the upper or lower gastrointestinal tract. The microbiome at different sites may share common elements as well as possessing distinct and characteristic members. The impression from the limited number of studies currently available is that each site may possess a surprisingly consistent core microbiome that is shared by most individuals. This consistency is likely to reflect almost completely unexplored host factors that actively manage the microbiome. In the place of a simplistic model that pathogens cause disease, microbial-induced injuries may now be understood in terms of complex changes in a dynamic and innately homeostatic community. Therefore, in this review, we discuss what is …

Año de publicación:

2015

Keywords:

Fuente:

google