The synthesis of naturally occurring peptides and their analogs


Abstract:

The number of peptide-based pharmaceuticals has increased enormously over recent years; some of these peptides are derived from natural sources, and many are large and complex. This review provides an overview of the current state of peptide synthesis methodology, focusing mainly on the synthesis of natural peptides and their analogs. © The Thomson Corporation.

Año de publicación:

2007

Keywords:

  • Total synthesis
  • Chemical ligation
  • biosynthesis
  • cyclic peptides
  • Acyl migration
  • resin
  • Pharmaceutical peptide
  • Solid phase
  • NRP
  • Unnatural amino acids
  • Pseudoproline

Fuente:

googlegoogle
scopusscopus

Tipo de documento:

Review

Estado:

Acceso restringido

Áreas de conocimiento:

  • Péptido
  • Bioquímica
  • Bioquímica

Áreas temáticas:

  • Química orgánica
  • Farmacología y terapéutica