The synthesis of naturally occurring peptides and their analogs
Abstract:
The number of peptide-based pharmaceuticals has increased enormously over recent years; some of these peptides are derived from natural sources, and many are large and complex. This review provides an overview of the current state of peptide synthesis methodology, focusing mainly on the synthesis of natural peptides and their analogs. © The Thomson Corporation.
Año de publicación:
2007
Keywords:
- Total synthesis
- Chemical ligation
- biosynthesis
- cyclic peptides
- Acyl migration
- resin
- Pharmaceutical peptide
- Solid phase
- NRP
- Unnatural amino acids
- Pseudoproline
Fuente:


Tipo de documento:
Review
Estado:
Acceso restringido
Áreas de conocimiento:
- Péptido
- Bioquímica
- Bioquímica
Áreas temáticas:
- Química orgánica
- Farmacología y terapéutica