Total synthesis of (±)-euryfuran through Ti(III) catalyzed radical cyclization

Abstract:

A concise total synthesis of the furano-sesquiterpene (±)-euryfuran, a bioactive metabolite from some marine sponges, is presepted. The key step is a highly diastereoselective titanium (III) catalyzed radical cyclization of a farnesol epoxyderivative. © 2007 Bentham Science Publishers Ltd.

Año de publicación:

2007

Keywords:

• Diastereoselectivity
• Farnesol
• Cyclization
• Furanosesquiterpenes
• titanium
• Radical reactions

Fuente:

scopus