Retraction:Two novel bioactive glucosinolates from Broccoli (Brassica oleracea L. var. italica) florets

Abstract:

Two novel glucosinolates along with one known glucosinolate were isolated from Broccoli (Brassica oleracea L. var. italica) florets. Their structures were established mainly by 1D (¹H and ¹³C NMR), 2D NMR ( ¹H-¹H COSY, DEPT 135°, HSQC and HMBC), and Tandem MS-MS spectrometric data as 2-mercaptomethyl sulfinyl glucosinolate [(Z)-4-(methylsulfinyl)-N-(sulfooxy)-2-((2′S,3′R,4′S, 5′S,6′R)-3′,4′,5′-trihydroxy- 6′(hydroxylmethyl)-2′-mercapto tetrahydro-2H-pyran-2-yl) butane amide] 1, (Z)-1-((2S,5S)-5-hydroxytetra-hydro-2H-pyran-2-ylthio)-2-(1H-indol-3- yl) ethylidene amino sulfate 2 and a known cinnamoyl [6′-O-trans- (4″-hydroxy cinnamoyl)4-(methylsulphinyl)butyl glucosinolate] 3. Compound 1 exhibited scavenging activity against DPPH with an inhibitory concentration IC<inf>50</inf> of 20 mM, whereas compound 3 was a weak antioxidant when compared to the standard quercetin (5 mM) as a positive control. Both the compounds showed a significant and similar antimicrobial activity against Staphylococcus aureus with an IC<inf>50</inf> of <625 μg/mL when compared to antibiotic duricef. Against Salmonella typhimurium the IC<inf>50</inf> of 1 and 3 was determined as <625 μg/mL and <1250 μg/mL, respectively, when compared to ampicillin (IC<inf>50</inf> ≤39 μg/mL) as a positive control. © 2012 Elsevier Ltd. All rights reserved.

Año de publicación:

2012

Keywords:

• antioxidant
• Glucosinolates
• Brassica oleracea L. var. italica
• Antimicrobial
• Tandem MS-MS and 1D and 2D NMR
• Antioxidant

Fuente:

scopus

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