Ultrasound promoted and SiO<inf>2</inf>/CCl<inf>3</inf>COOH mediated synthesis of 2-aryl-1-arylmethyl-1H-benzimidazole derivatives in aqueous media: An eco-friendly approach

Abstract:

Ultrasonic irradiation is an efficient and innocuous technique of reagent activation for synthesizing organic compounds. First one-pot synthesis of 2-aryl-1-arylmethyl-1H- benzimidazole derivatives from o- phenylenediamine and an aromatic aldehyde in the presence of silica gel supported trichloroacetic acid (SiTCA) was carried out with excellent yields at 50°C by sonication. This method provided several advantages such as green solvent, inexpensive catalyst, simple experimental methodology, shorter reaction time and higher yield.

Año de publicación:

2014

Keywords:

• silica gel supported trichloroacetic acid (SiTCA)
• ultrasound irradiation
• One-pot synthesis
• regioselective
• 2-Aryl-1-arylmethyl-1H-benzimidazoles

Fuente:

scopus

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