Ultrasound-assisted one-pot, four component synthesis of 4-aryl 3,4-dihydropyridone derivatives

Abstract:

The condensation of Meldrum's acid, aromatic aldehydes, alkyl acetoacetates and ammonium acetate in glacial acetic acid under ultrasound irradiation at room temperature results in the formation of 3,4-dihydropyridone derivatives (4a- p) in 85-96% yields. Compared with conventional methods, the main advantages of the present procedure are milder conditions, shorter reaction times and higher yields. © 2010 Elsevier B.V.

Año de publicación:

2011

Keywords:

• Sonochemistry
• ultrasound irradiation
• 3,4-Dihydropyridone derivatives

Fuente:

scopus

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