A flexible method for the fabrication of gold nanostructures using oligonucleotide derivatives

Abstract:

Several linear and branched DNA structures from 80-200 nm with a biotine molecule in the middle have been prepared. These structures have been decorated by addition of positively charged gold nanoparticles carrying 4-(dimethylamino)pyridine ligands. Streptavidin binds to the central biotine molecule introducing a 20 nm gap in the structure in which a biotinylated nanoparticle can be introduced. The simplest structure (80 nm, linear) is formed by 4 oligonucleotides. By changing some of these components changes on length, shape, and recognition system easily can be introduced. Copyright © Taylor & Francis Group, LLC.

Año de publicación:

2007

Keywords:

• Gold nanoparticles
• self-assembly
• DNA nanobiotechnology

Fuente:

scopus