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Brain-heart: first case report of simultaneous toxicity of 5-fluorouracil

Abstract:

Initial laboratory results revealed elevated troponins (37.66 ng/L) and 42.84 ng/L at 1 hour. Electrocardiogram at 1 hour with ST-segment correction. Prohormone of brain natriuretic peptide (pro-BNP) at 678 pg/mL. The patient was managed in the intensive care unit for hemodynamic and neurological stabilization. The echocardiogram on admission showed mild apical hypokinesia with decreased STRAIN in that region (Fig. 1A), and the left ventricular ejection fraction (LVEF) was 71%. SCORE2-OP Cardiovascular risk was estimated at 5.8%. GRACE 122