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The effect of fatty acids on the developmental direction of Strongyloides ratti first-stage larvae

Abstract:

The effect of fatty acids was studied on the developmental direction of Strongyloides ratti first-stage larvae (L<inf>1</inf>). The proportion of third-stage infective larvae increased markedly when Lj were cultured in faeces with added fatty acids such as palmitic (C<inf>16</inf>), stearic (C<inf>18</inf>), oleic (C<inf>18:1</inf>) and linoleic (C<inf>18:2</inf>) acids. Unsaturated fatty acids were more effective than saturated ones. Moreover, the proportion of infective larvae increased with quantity of linoleic acid but the triacylglycerols of any fatty acid had no effect. These results suggest that these free fatty acids cause physiological changes that determine the developmental course of L<inf>1</inf> of S. Ratti in nature. © 1989, School of Business Administration, University of Washington. All rights reserved.