Association between the expression of miR‐26 and goat milk fatty acids

Abstract:

Contents microRNA (miRNA) are small noncoding RNA that regulate protein abundance and are involved in diverse aspects of cellular function including aspects of lipid metabolism in mammary gland of ruminants. Although our previous studies showed that the miR‐26 family and its host genes control components of the cellular fatty acid metabolic machinery in goat mammary epithelial cells, a direct relationship between the miR‐26 family and milk fatty acids remains unknown. Bioinformatics analysis in this study indicated that the miR‐26 family targets belong to the PI3K‐Akt signalling pathway, MAPK signalling pathway, and fatty acid biosynthesis pathway. Studies on the relationship of miR‐26 family and their host genes with milk composition during mid‐lactation revealed that the expression of the miR‐26 family and their host genes were associated with total fat yield and short‐chain, medium‐chain and long …

Año de publicación:

2018

Keywords:

Fuente:

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